Milk Calcium, Magnesium + Combination Tablets

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Therapeutic Indication

Prevention and treatment of osteoporosis
Improves bone strength and density
Supports calcium absorption and utilization
Promotes cardiovascular health by preventing arterial calcification
Boosts immunity and collagen synthesis
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Milk Calcium, Magnesium + Combination

Tablet

Milk calcium, a concentrated source of calcium and other minerals derived from milk. Besides calcium, it includes minerals important for bone growth such as phosphorus, magnesium, potassium, sodium, iron, and zinc. Phosphorus is needed for effective calcium absorption and bone repair. Researchers found that an increase in bone mass in pre-pubertal girls whose diets were supplemented with milk calcium lasted several years after the study even without further supplementation. An adequate intake of calcium is clearly essential in achieving and maintaining sufficient bone mass due to the simple fact that calcium, in the form of hydroxyapatite, constitutes the major part of the bone structure. In combination with vitamin D it is effective in preventing bone loss and fractures.


Magnesium About half of the total magnesium (Mg2+) of the body exists in bone. Bone is one of the main Magnesium pools in the body. Epidemiologic studies have demonstrated a positive correlation between magnesium intake and bone mineral density. It is also reported in a study that magnesium deficiency induced a decrease in osteoblasts number, an increase in osteoclasts number and a decrease in bone strength. In contrast, dietary magnesium supplementation improved bone formation, bone resorption and bone strength. Magnesium also helps in producing an alkaline environment, reducing calcium excretion and thus improving bone density. Magnesium deficiency is known as a risk factor for osteoporosis, since it is essential mineral for normal bone growth.

Vitamin C: It promotes higher bone mass and lowers fracture rates. It has a dual action on bone renewal. This happens because Vitamin C suppresses osteoclasts (bone-destroying cells) while it also stimulates the production of osteoblasts (bone-building cells). Vitamin C promotes healthy and constant bone renewal, critical to preventing fractures.
Zinc: It is an important mineral that is required for normal bone development. It increases both the number and area of mineralized bone nodules. Zinc has biphasic effects on the differentiation and mineralization of human osteoblast-like cells. A low dietary intake of zinc and accompanying low blood levels has been associated with an increased risk of osteoporosis in both women and men.
Vitamin D3 It is essential for maximizing bone health. Vitamin D3 enhances intestinal absorption of calcium and phosphorus. Season, latitude, skin pigmentation, sunscreen use, clothing and aging can dramatically influence the synthesis of vitamin D3 in the skin. This deficiency is very prevalent in osteoporotic patients. Vitamin D3 deficiency causes osteopenia, osteoporosis and osteomalacia, increasing the risk of fracture. Vitamin D3 deficiency causes muscle weakness, increasing the risk of falls and fractures. Patients being suffering from osteoporosis should be adequately supplemented with calcium and vitamin D3 to maximise the benefit of treatment. Vitamin D3 insufficiency is highly prevalent among postmenopausal women with osteoporosis and in the elderly. Supplements of vitamin D3 (cholecalciferol) may decrease falls and fracture risk by 25%. The hormone calcitonin promotes the transfer of calcium into the bones, while parathyroid hormone (PTH) promotes the release of calcium from the bones. Vitamin D is important in controlling PTH level with a deficiency leading to higher PTH concentration and subsequent demineralization.

Menaquinone (Vitamin K2): Vitamin K2 is produced by bacteria. It is present in high quantities in our gut, but unfortunately is not absorbed from there and passes out in stool. Vitamin K2 directs calcium to your skeleton, while preventing it from being deposited where you don't want it - i.e., your organs, joint spaces, and arteries. A large part of arterial plaque consists of calcium deposits (atherosclerosis), hence the term "hardening of the arteries."
The main role of vitamin K is to act as a cofactor for the conversion of glutamate into gamma-carboxyglutamate, which, in turn, is involved in the synthesis of osteocalcin (produced by osteoblasts), the hormone that promotes bone formation. Osteocalcin also appears to help prevent calcium from depositing into your arteries. So while increasing calcium is good for your bones, it is not so good for your arteries, which can become calcified. Vitamin K helps protect your blood vessels from calcifying when in the presence of high calcium levels. Vitamin D helps your body to absorb calcium, but vitamin K directs that calcium to your skeleton where it's needed. Without the help of vitamin K2, the calcium that your vitamin D so effectively lets in might be working AGAINST you - by building up in your coronary arteries rather than your bones. The safety of vitamin D is dependent on vitamin K, and that vitamin D toxicity (although very rare with the D3 form) is actually caused by vitamin K2 deficiency.

Speciality Bone Health | Immunity | Cardiovascular Support
Tags Osteoporosis Prevention | Calcium Supplement | Heart Health
Strength
  • Milk Calcium 500 mg
  • Magnesium 100 mg
  • Vitamin C 50 mg
  • Vitamin D3 50 mcg
  • Zinc 7.5 mg
  • Menaquinone (Vitamin K2) 45 mcg
Packing Size
  • 10 Tablets

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Mechanism

Calcium and Magnesium provide structural support for bones and muscles. Vitamin D3 enhances intestinal calcium absorption. Vitamin K2 (Menaquinone) activates osteocalcin, directing calcium into bones and away from arteries. Vitamin C supports collagen synthesis, essential for bone matrix and immunity.

Pharmacokinetics

  • Calcium: Absorbed in small intestine, regulated by Vitamin D3.
  • Magnesium: Absorbed in ileum and jejunum, widely distributed.
  • Vitamin C: Rapid absorption, metabolized in liver, excreted in urine.
  • Vitamin D3: Fat-soluble, absorbed with dietary fats, stored in liver and fat tissue.
  • Vitamin K2: Absorbed in small intestine, incorporated into lipoproteins, metabolized in liver.

Side Effects

  • Mild gastrointestinal upset (constipation, bloating)
  • Hypercalcemia with excessive intake
  • Rare allergic reactions
  • Kidney stone risk with prolonged high-dose calcium

Contraindication

  • Hypersensitivity to any component
  • Severe renal impairment
  • Hypercalcemia or hypervitaminosis D
  • Patients on anticoagulant therapy (Vitamin K2 caution)

Interaction

  • Calcium may reduce absorption of certain antibiotics (tetracyclines, fluoroquinolones).
  • Vitamin D3 may interact with corticosteroids and anticonvulsants.
  • Vitamin K2 may reduce efficacy of anticoagulants (warfarin).
  • Magnesium may interact with diuretics and proton pump inhibitors.

Warning and Precautions

  • Use under medical supervision in patients with neuropathy or seizure disorders.
  • Monitor renal function during long-term therapy.
  • Avoid abrupt discontinuation to prevent rebound seizures.
  • Store at 25°C; excursions permitted to 15–30°C.
  • Keep out of reach of children.

Dosage

As directed by the Dietician.